When colonel john jacob astor iv debuted this fifth avenue hotel in 1904 he set a new standard for luxury more than a century later astors vision continues to delight located at the corner of fifth avenue and west 55th street the st regis new york is one of the jewels of midtown manhattan famous neighbors include rockefeller center tiffany co and the glorious st patricks cathedral all within 5 blocks debeers occupies the corner of the hotels first floor the museum of modern a